An AC electrothermal self-circulating system with a minimalist process to construct a biomimetic liver lobule model for drug testing.

The measured electrical conductivity of the culture medium which contains 40% DMEM and 40% RPMI supplemented with 1% P/S and 10% FBS shows an increasing trend from 1.12 to 1.43 S m −1 for 3.5 d.

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