Contributions of the Catechol-O-Methyltransferase Val158Met Polymorphism to Changes in Brain Iron Across Adulthood and Their Relationships to Working Memory.

Front Hum Neurosci · 2022 · PMC9091601 · PMID 35571998

Europe PMC DOI

hedged sentence

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

marginally significantp = 0.056so close (0.05 < p ≤ 0.1)

In comparison, when contrasting Met and Val homozygotes, COMT effect on baseline iron was not significant (β = −0.198, p = 0.37), whereas the effect on iron accumulation was marginally significant (β = −0.496, p = 0.056).

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