Omeprazole Administration in Preterm Preeclampsia: a Randomized Controlled Trial to Study Its Effect on sFlt-1 (Soluble Fms-Like Tyrosine Kinase-1), PlGF (Placental Growth Factor), and ET-1 (Endothelin-1).

Moreover, in our former analysis evaluating PPI users, a nonsignificant trend toward higher intubation rate was similarly observed in the non-PPI group compared with the PPI group (15% versus 5%, P =0.07). 7 On the other hand, in the trial by Cluver et al, 11 where a much larger population was evaluated, a difference in intubation rate between esomeprazole and placebo group was not found.

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