Hepatic decompensation is accelerated in patients with cirrhosis and alpha-1 antitrypsin Pi∗MZ genotype.

JHEP Rep · 2022 · PMC9097455 · PMID 35571533

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

trending toward significancep = 0.065so close (0.05 < p ≤ 0.1)

The association was significant for ascites (HR 1.82, 95% CI 1.09-3.05, p = 0.022) and trending toward significance for hepatic encephalopathy (HR 1.54, 95% CI 0.97-2.43, p = 0.065), and was directionally consistent for variceal bleeding though there were few incident events (n = 40 with incident events >6 months after follow-up).

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