Analyzing nested experimental designs-A user-friendly resampling method to determine experimental significance.

PLoS Comput Biol · 2022 · PMC9098003 · PMID 35500032

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may be significantno p-value reported

If the researcher suspects there may be significant heterogeneity in treatment effects—perhaps the donor mice are heavily outbred, or the donors are humans–they can incorporate this heterogeneity as an interaction effect ( Fig 7A ) [ 44 ].

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