MIC1-3 gene knockout induced a strong humoral and cellular Th1 response and induced highly significant protection against chronic infection (>96% reduction in cysts in brain tissue) and congenital toxoplasmosis (fewer infected fetuses in vaccinated groups compared with non-vaccinated (4.6% vs. 33.3%)) [ 105 ].
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Mining the Proteome of <i>Toxoplasma</i> Parasites Seeking Vaccine and Diagnostic Candidates.
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