The inverse fluctuation of circulating sRAGE and free AGEs observed here, and the more or less significant inverse correlations observed by the pioneering study of Miranda et al. are far from proof that sRAGE traps circulating free AGEs and eliminates them.
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Plasma Levels of Free <i>N</i><i><sup>Ɛ</sup></i>-Carboxymethyllysine (CML) after Different Oral Doses of CML in Rats and after the Intake of Different Breakfasts in Humans: Postprandial Plasma Level of sRAGE in Humans.
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