Globally elevated excitation-inhibition ratio in children with autism spectrum disorder and below-average intelligence.

A paired t test revealed a highly significant and strong decrease in the mean slope from the EO to EC condition in the combined group of subjects ( T (82) = 5.81, p < 0.000001, Cohen d = 0.64), as well as in the separate groups (TD: T (44) = 3.67, p = 0.0006, Cohen d = 0.55; ASD >85 : T (22) = 3.38, p = 0.0003, Cohen d = 0.71; ASD <85 : T (14) = 3.31, p = 0.005, Cohen d = 0.85; Fig. 2 D).

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