AOM/DSS Induced Colitis-Associated Colorectal Cancer in 14-Month-Old Female Balb/C and C57/Bl6 Mice-A Pilot Study.

Int J Mol Sci · 2022 · PMC9104960 · PMID 35563665

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highly significantno p-value reported

In C57/Bl6 mice, we observed a highly significant positive correlation between the concentrations of DSS in the drinking water and both histology score and the percentage of Ki67 positive cells, indicating that the amount of DSS administered to these animals significantly affected both colon remodeling/development of malignancy and cell proliferation.

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