Placental Transcription Profiling in 6-23 Weeks' Gestation Reveals Differential Transcript Usage in Early Development.

Int J Mol Sci · 2022 · PMC9105363 · PMID 35562897

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Multiple highly significant transcripts from the claudin gene family, which mediate angiogenesis and trophoblast invasion [ 32 ], were found to be down-regulated in mid gestation ( CLDN10-002 , CLDN10-001 , CLDN6-201 , CLDN7-003 , and CLDN3-001 ), with only CLDN1-001 found to be upregulated.

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