Folic Acid Levels During Pregnancy Regulate Trophoblast Invasive Behavior and the Possible Development of Preeclampsia.

Front Nutr · 2022 · PMC9106796 · PMID 35578613

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highly significantp < 0.01actually significant

A highly significant negative correlation was observed between global methylation and LINE1 promoter methylation in JEG-3 cells upon folic acid supplementation (r = −1, p < 0.01), global methylation also showed a significant positive correlation with DNMT3A (r = 0.99, p < 0.05) ( Table 2 ).

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