Cancer suppression and the evolution of multiple retrogene copies of TP53 in elephants: A re-evaluation.

Evol Appl · 2022 · PMC9108310 · PMID 35603034

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However, the test for positive selection at individual codon sites (PAML model M1 and M2) was highly significant (χ 2 = 10.66 with 2 df , p = 0.005), identifying two codons subject to selection (dn/ds > 1), codon #1 (dn/ds = 3.71; p = 0.015) and codon #16 (dn/ds = 3.65; p = 0.034; see Figure 1 ).

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