<i>Mycobacterium tuberculosis</i> Induces <i>Irg1</i> in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis.

Front Cell Infect Microbiol · 2022 · PMC9109611 · PMID 35586249

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highly significantno p-value reported

In contrast we detected a partial but highly significant reduction in Irg1 expression in Mtb exposed MyD88, NF-κB and TLR-2 but not TLR4 or TLR-9 deficient macrophages.

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