Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy.

DystromiRs All three dystromiRs were markedly elevated in DE50-MD serum ( Figure 5 ): under linear mixed model analysis, genotype was highly significant (P<0.0001) for all three miRs, while the effect of time was not significant for any (though a modest interaction of genotype and time was detected).

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