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<i>In Vitro</i> Activity of Ertapenem against Neisseria gonorrhoeae Clinical Isolates with Decreased Susceptibility or Resistance to Extended-Spectrum Cephalosporins in Nanjing, China (2013 to 2019).

Antimicrob Agents Chemother · 2022 · PMC9112910 · PMID 35491832

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an increasing trendno p-value reported
The proportion of isolates with increased ertapenem MICs (MICs of ≥0.125 mg/L) showed an increasing trend during the study period in the absence of clinical use, which may have been the result of the yearly increase in the proportion of isolates that contained the penA mosaic allele, also shown in our study.

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