Exposure-Efficacy Analyses Support Optimal Dosing Regimens of Ceftolozane/Tazobactam in Participants with Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia in ASPECT-NP.

After generation of individual exposure estimates based on the population PK models, the planned procedures for exposure–efficacy model development included graphical data exploration to assess whether there was an apparent trend between exposure measures and primary and key secondary efficacy endpoints.

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