Interestingly, in the responder dogs, a correlation between an increased IgG binding and the overall survival was observed, with statistical significance for Do–D2 responders ( figure 2D, E ) and a reliable trend for Do–D3 responders ( figure 2I, J ).
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Antigen mimicry as an effective strategy to induce CSPG4-targeted immunity in dogs with oral melanoma: a veterinary trial.
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Moreover, a positive trend between an increased antibody level and a prolonged DFI, considering the local recurrences, was found for the responder dogs to Do–D2 ( online supplemental figure S7C, D ), but not for those to Do–D3 ( online supplemental figure S7G, H ).