Regulation mechanisms of flavonoids biosynthesis of Hancheng Dahongpao peels (Zanthoxylum bungeanum Maxim) at different development stages by integrated metabolomics and transcriptomics analysis.

There is an increasing trend of the acacetin-o-glucuronic acid, apigenin-7,4′-dimethylether and eriodictiol-o-rhamnoside-o-pentoside-o-glucuronate throughout the development process, whereas the naringenin-7-o-triglycoside, 6,7,8-trihydroxy-5-methoxyflavone and hesperetin were decreased in the Y-vs-R peels. 6,7,8-trihydroxy-5-methoxyflavone and hesperetin demonstrated significantly higher accumulation in the yellow stage, and apigenin-7,4′-dimethylether had the highest content in the full red stage.

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