highly significantp < 0.001
Whole-brain investigation with a cluster-defining threshold of p < 0.01 revealed a highly significant reduction of relative brain volume covering striatum (bilateral cluster, p < 0.001, cluster-corrected), hippocampus (bilateral cluster, p < 0.001, cluster-corrected) and olfactory bulb ( p < 0.01, cluster-corrected) in DAT-KO rats (Fig. 2A ).