References eLife eLife 10.7554/eLife.77646.sa0 Editor's evaluation Hinnebusch Alan G Reviewing Editor 1 1 Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States The findings in this report are highly significant in providing evidence that a positive feedback loop exists between Sfl1-dependent interaction with the nuclear pore complex and H3K4me2 deposition in the INO1 promoter, which is essential for recruitment of poised Pol II, but which does not require transcription initiation to occur.
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Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates <i>INO1</i> transcriptional memory.
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