Replacing 4-hydroxyphenyl with 3-hydroxyphenyl at position R 2 was also studied ( 6e vs 6f and 6m vs 6j ), although a definite trend could not be observed with the limited data at hand.
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Design, synthesis and evaluation of amino-3,5-dicyanopyridines and thieno[2,3-b]pyridines as ligands of adenosine A<sub>1</sub> receptors for the potential treatment of epilepsy.
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