Triple-serotype chimeric oncolytic adenovirus exerts multiple synergistic mechanisms against solid tumors.

J Immunother Cancer · 2022 · PMC9131115 · PMID 35609942

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highly significantno p-value reported

In the NCG mouse model of human prostate cancer Du145 cells, OncoViron combined with CAR T-cell therapy had highly significant therapeutic effects; the expressed cytokines prolonged the survival of CAR T and promoted CAR T-cell proliferation and infiltration in TME.

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