Imaging the effect of ketamine on synaptic density (SV2A) in the living brain.

Mol Psychiatry · 2022 · PMC9133063 · PMID 35165397

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

just outside significancep =0.054so close (0.05 < p ≤ 0.1)

However, in the ‘SV2A deficit’ group, SV2A density was significantly higher 24 hours after ketamine administration in dlPFC (8.7% higher, p =0.046, d=1.1) and ACC (10.4% higher, p =0.035, d=1.2), and was just outside significance in the hippocampus (7.0% higher, p =0.054, d=1.0; Figure 3B ).

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