For quality of life, significant beneficial effects of the exercise intervention were found for the EORTC QLQ C-30 summary score (B3.96, 95% CI 1.12;6.75), global health status (B5.82, 95% CI 1.09; 10.57), role functioning (B7.17, 95% CI 1.27; 13.06), social functioning (B5.95, 95% CI 0.22; 11.62), and with borderline significance on the cognitive functioning scale (B4.99, 95% CI − 0.37; 10.35) (Fig. 4 and Additional file 1 : Table S7).
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Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer: a randomized controlled trial (PAM study).
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Post hoc analyses for level of fatigue showed beneficial effects of exercise for the highly fatigued patients, on Wordlist Learning (B4.36, 95% CI 0.47; 8.25) and Reaction Time (B-26.7, 95% CI − 52.9; − 0.6), and a borderline significant improvement on Wordlist Recognition (B0.96, 95% CI − 0.06; 1.98) (Fig. 3 and Additional file 1 : Table S6).