Podoplanin Expression Independently and Jointly with Oral Epithelial Dysplasia Grade Acts as a Potential Biomarker of Malignant Transformation in Oral Leukoplakia.

Biomolecules · 2022 · PMC9138639 · PMID 35625534

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

marginal significancep = 0.054so close (0.05 < p ≤ 0.1)

In the multivariate analysis, we observed that podoplanin score (with combination of extent and intensity) presented an independent association on the risk of transformation to oral cancer ( p = 0.017; HR of 10.148, 95% CI of 1.503–68.532), while binary dysplasia grade reached marginal significance ( p = 0.054; HR of 9.316, 95% CI of 0.965–89.951).

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