BDNF and Pro-BDNF in Amyotrophic Lateral Sclerosis: A New Perspective for Biomarkers of Neurodegeneration.

Brain Sci · 2022 · PMC9139087 · PMID 35625004

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0549

boldest claim

The sentences

highly significantp < 0.0001actually significant

In particular, the difference was highly significant in the case of ALS (controls: 9098.68 ± 1210.76 pg/mL; ALS: 17,235.3 ± 1033.2; p < 0.0001), and AD (18,496.00 ± 1165.27; p < 0.001) and less in the case of ID (16,180.35 ± 1323.65; p = 0.004).

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of borderline significancep = 0.05486so close (0.05 < p ≤ 0.1)

Pro-BDNF levels in patients with BMI < 25 were of borderline significance ( p = 0.05486) when compared with the controls, while the significance was evident in the group with BMI > 25 ( p < 0.001).

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