Barely Significant
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Modification Effect of <i>PARP4</i> and <i>ERCC1</i> Gene Polymorphisms on the Relationship between Particulate Matter Exposure and Fasting Glucose Level.

Int J Environ Res Public Health · 2022 · PMC9140444 · PMID 35627777

3
hedged sentences
0.0812
closest p · 1.6× alpha
0.0812
boldest claim

The sentences

marginal significancep = 0.0812so close (0.05 < p ≤ 0.1)
PM Concentrations and Their Correlations In the comparison of PM 10 , PM 2.5–10 , and PM 2.5 concentrations among lag days, PM 10 and PM 2.5–10 concentrations were significantly different among lag days for both original and log-transformed concentrations ( p < 0.05 for all), while PM 2.5 concentrations were not significantly different among lag days; although, original values showed marginal significance ( p = 0.0812) ( Figure 1 ).

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an increasing trendno p-value reported
Because the G allele for rs12863638, C allele for rs3783073, and G allele for rs2275660 of PARP4 and T allele for rs11615 and C allele for rs3212961 of ERCC1 showed an increasing trend for the susceptibility to PMs exposure and there were strong linkages among SNPs of same gene, we evaluated the relationship between PMs exposure and glucose level by combined diplotypes of PARP4 and ERCC1 .

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marginally significantno p-value reported
Participants with G allele for rs12863638, C allele for rs3783073, G allele for rs2275660, T allele for rs11615, and C allele for rs3212961 seemed to be susceptible to exposure to three PMs in relation to the increase in glucose level, although the ERCC1 TT genotype for rs11615 was marginally significant with the greatest effect size ( Table 4 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.