Polyploid giant cancer cells are dependent on cholesterol for progeny formation through amitotic division.

Sci Rep · 2022 · PMC9142539 · PMID 35624221

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highly significantno p-value reported

As in PPC1 prostate cancer cells, we detected a highly significant increase in INSIG1 mRNA and a smaller, but also significant increase in HMGCR following ASAH1 inhibition in PGCC (Fig. 3 d).

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