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Neurogenesis Is Increased in Human Neural Stem Cells by Aβ40 Peptide.

Int J Mol Sci · 2022 · PMC9143763 · PMID 35628629

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an increasing trendno p-value reported
The results we obtained by RT-qPCR showed an increasing trend in the CCND1 mRNA levels (coding for cyclin D1 and involved in cell proliferation) in hNS1 cells treated with the Aβ40 peptide (1 μM), as well as a statistically significant increase in the NEUROD1 mRNA levels (coding for NeuroD1 and involved in neuronal maturation) in cells treated with the Aβ40 peptide (0.5 μM and 1 μM) compared to the control hNS1 cells (vehicle) ( Figure 3 G).

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