Novel Oxime Synthesized from a Natural Product of <i>Senecio nutans</i> SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism.

In this line, the contractile response to PE was tested and both compounds significantly reduced the contractile response to PE, although oxime–1 showed a more highly significant ( p < 0.001) reduction of the contractile response to different concentrations of PE (10 −7 to 10 −5 M).

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