The Role of IgG Fc Region N-Glycosylation in the Pathomechanism of Rheumatoid Arthritis.

Int J Mol Sci · 2022 · PMC9146365 · PMID 35628640

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highly significantno p-value reported

Remarkably, we could not detect an association of TNFα production with the level of sialylation; however, in the set of 77 glycovariants analyzed, we identified one glycopeptide with the structure of N4H3, which showed a highly significant negative correlation with the TNFα-inducing capacity.

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