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A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases.

Pharmaceuticals (Basel) · 2022 · PMC9146999 · PMID 35631391

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an increasing trendno p-value reported
There was an increasing trend in ADR reporting every year for all five ADs with peaks in 2014 ( Figure 1 ).

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