Other highly significant downregulated genes include the GTP cyclohydrolase 1 gene ( Gch1 ), responsible for the production of a TH cofactor, nicotinic cholinergic receptors (cholinergic receptor nicotinic alpha 4 subunit; cholinergic receptor nicotinic alpha 6 subunit; neuronal acetylcholine (nicotine) receptor subunit beta-3), genes associated with synaptic vesicle exocytosis such as complexin 1 and 2 genes, neuron-derived neurotrophic factor, and the peptide guanylate cyclase 2c ( Gucy2c ).
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Early Life Social Stress Causes Sex- and Region-Dependent Dopaminergic Changes that Are Prevented by Minocycline.
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