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Level and trend of total plasma cholesterol in national and subnational of Iran: a systematic review and age-spatio-temporal analysis from 1990 to 2016.

J Diabetes Metab Disord · 2022 · PMC9150051 · PMID 35668771

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an increasing trendno p-value reported
A pooled analysis of national self-reported surveys in Switzerland indicated an increasing trend of treatment coverage and effective treatment in last decades and reaching to 38.8% and 75.1%, respectively [ 66 ].

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a decreasing trendno p-value reported
Previous evidence shows a decreasing trend of raised total cholesterol (TC) and the burden attributable to it globally and in high-income regions, but the trends in a number of developing regions such as east and southeast Asia are increasing and in many other low- and middle-income regions, trends are uncertain [ 7 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.