Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum.

Enrichment in genes expressed in the adrenal gland for TS-ADHD-ASD was also highlighted, reaching borderline significance ( p = 1.89 × 10 −3 , with a significance threshold of p < 1.67 × 10 −3 ) ( Figures S2 and S3 in Supplement 1 ; Table S10 in Supplement 2 ).

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We found significant enrichment in pituitary and hypothalamus expression, and furthermore, the enrichment of adrenal gland expression was also borderline significant.

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