Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content.

BMC Cancer · 2022 · PMC9164347 · PMID 35655145

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a decreasing trendno p-value reported

Significantly lower LINE-1 methylation was found in TA (73.8 ± 4.1%) and TVA (69.8 ± 4.5%) in comparison with N samples (77.5 ± 1.7%) ( p ≤ 0.05), and a decreasing trend was observed in TVA (69.8 ± 4.5%) vs.

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