Sirt1 protects against hippocampal atrophy and its induced cognitive impairment in middle-aged mice.

BMC Neurosci · 2022 · PMC9169381 · PMID 35668361

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a decreasing trendno p-value reported

Compared with the control group, the total hippocampal volume and each subregion volume in the sham group showed a decreasing trend, but there was no statistical difference, which might be a slight effect caused by stereotactic injection.

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