The low copies of HSV-1 transcripts in a given single cell may not be significant; it has been shown both clinically and preclinically that HSV-1 latency is common in our general population without causing detrimental consequences in brain health ( Readhead et al., 2018 ).
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Simultaneous Detection of Herpes Simplex Virus Type 1 Latent and Lytic Transcripts in Brain Tissue.
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