highly significantp = 0.009
This difference was most evident in the earlier stage group (stage 1 to 2) with median overall survival of 30.0 months (95% CI: 26.4 to 35.1 months) in the warfarin group compared to 23.7 months (95% CI: 19.6 to 31.8 months) in the DOAC group, yielding a highly significant HR of 1.24 (95% CI: 1.06 to 1.45, p = 0.009).