55 The urease inhibition efficiency of (4) was calculated by using optical densities in the absence (OD control ) and presence of sample (OD sample ) in the following formula: 4 The compound (4) has shown highly significant urease inhibitory efficiency with IC 50 ± SEM value of 0.0389 ± 0.0017 μM as compared to thiourea used as the standard inhibitor (18.2 ± 0.297 μM).
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Structure and surface analyses of a newly synthesized acyl thiourea derivative along with its <i>in silico</i> and <i>in vitro</i> investigations for RNR, DNA binding, urease inhibition and radical scavenging activities.
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