Paclitaxel and cisplatin combined with concurrent involved-field irradiation in definitive chemoradiotherapy for locally advanced esophageal squamous cell carcinoma: a phase II clinical trial.

Radiat Oncol · 2022 · PMC9185874 · PMID 35681233

Europe PMC DOI

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0.1040

closest p · 2.1× alpha

0.1040

boldest claim

The sentences

an increasing trendP = 0.104not close (p > 0.1)

A small-sample-size trial, RTOG 0113, compared paclitaxel-based regimens with the cisplatin plus fluorouracil regimen from the RTOG 9405 trial in dCRT for patients with locally advanced esophageal cancer, and showed that the paclitaxel-based chemotherapy regimen had an increasing trend in 1-year OS rate (76% vs 69%, P = 0.104) [ 8 , 9 ].

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