Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype.

PNAS Nexus · 2022 · PMC9186046 · PMID 35707206

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Q-PCR of mitochondrial genes in freshly isolated murine WT and Aldh3a1 –/– SSPC showed an overall trend of reduced gene expression, with a statistically significant difference noted in some candidate genes (mt-Nd2, mt-Nd3, and mt-Nd4; Figure S4B, Supplementary Material ).

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