Barely Significant
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Axonal injury in asymptomatic individuals preceding onset of multiple sclerosis.

Ann Clin Transl Neurol · 2022 · PMC9186135 · PMID 35502756

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an increasing trendno p-value reported
Results Loess regression of log sNfL for ratios between individual pre‐MS and matched control values as a function of time to MS onset showed an increasing trend from at least 10 years before MS onset (Fig. 1A ).

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