Barely Significant
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Clinical benefit of cancer drugs approved in Switzerland 2010-2019.

PLoS One · 2022 · PMC9187080 · PMID 35687539

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an encouraging trendno p-value reported
However, there is an encouraging trend that more recent registration trials evaluate HRQoL more often as a secondary outcome than this was done in older registration trials.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.