In that case, the sex-combined EXACT test p = 6.41E-61 (using the R program HardyWeinberg v1.7.4 [ 59 ]), but this highly significant Exact HWD testing result is due to the significant sdMAF alone.
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Major sex differences in allele frequencies for X chromosomal variants in both the 1000 Genomes Project and gnomAD.
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