In the UK cohort, the crude rate of hydroxyzine initiation was gradually increasing during the 24 months prior to the UK advisories, but following the advisories, the rate of hydroxyzine initiation dropped steeply before resuming an increasing trend (Fig. 2 ).
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Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study.
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