Abrogation of Notch Signaling in Embryonic TECs Impacts Postnatal mTEC Homeostasis and Thymic Involution.

Front Immunol · 2022 · PMC9189879 · PMID 35707539

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highly significantno p-value reported

However, ICN1 + mTEC numbers increased significantly by 3 months, and up to 4-fold by 5 months ( Figure 3D ), confirming a highly significant age-dependent upregulation of Notch1 activation in postnatal mouse mTECs.

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