Comparison of Bone Mineral Density in US Adults With Diabetes, Prediabetes and Normoglycemia From 2005 to 2018.

After multivariable adjustment, we found an increasing trend of BMD at the total hip, femoral neck, and lumbar spine with glucometabolic conditions from NGR and prediabetes to diabetes in adults aged ≥ 40 years in the US.

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Association of Glucose Status and BMD We found a positive trend for glucose status and BMD in the total hip, femoral neck, and lumbar spine (all P -trend <0.05) after the adjustment of three models (model 3: β=0.011, 95% CI: 0.004–0.018 for prediabetes; β=0.022, 95% CI: 0.012–0.031 for diabetes in the total hip; β=0.007, 95% CI: 0.001–0.015 for prediabetes; β=0.015, 95% CI: 0.006–0.025 for diabetes in the femoral neck; β=0.002, 95% CI: –0.008–0.012 for prediabetes; β=0.020, 95% CI: 0.007–0.033 for diabetes in the lumbar spine).

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