Model-informed drug development of voxelotor in sickle cell disease: Exposure-response analysis to support dosing and confirm mechanism of action.

CPT Pharmacometrics Syst Pharmacol · 2022 · PMC9197532 · PMID 35447017

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

may not be significantno p-value reported

However, the confidence intervals (CIs) around the local regression show some overlap between subcategories, suggesting that the change in slope may not be significant.

also in 2,774 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.