Barely Significant
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Evidence for a Prehypertensive Water Dysregulation Affecting the Development of Hypertension: Results of Very Early Treatment of Vasopressin V1 and V2 Antagonism in Spontaneously Hypertensive Rats.

Front Cardiovasc Med · 2022 · PMC9198251 · PMID 35722114

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a mild trendno p-value reported
There was no significant difference in 24-h urinary sodium excretion, even if a mild trend toward a reduced sodium excretion was observed in young SHR; fractional excretion of sodium (FENa) was not changed.

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